Abstract
Summary
Glycolysis reduces both glycogen fractions of the rat heart at about the same rate for the first 5 minutes, regardless of the medium used for suspension of the tissue. In Krebs Phosphate Ringer's solution and in unoxygenated 5.4% glucose, the 2 glycogens drop to a low, but stable level. The glycogen synthesized in the sugar medium is primarily the TCA soluble glycogen. The TCA. soluble glycogen begins synthesis at the end of 22.5 minutes and synthesis of the TCA insoluble fraction begins 50 minutes later. A distinct species difference was observed in the metabolism of cardiac glycogen in the rat and dog, inasmuch as the TCA insoluble fraction was relatively more stable in the dog.
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