Electrophoretic Distribution of Hexosamine in Plasma Proteins of the Rat Following Thyroidectomy. ∗

Abstract

Summary

Following thyroidectomy the rat develops a relative increase in gamma globulin. The increase in total plasma hexosamine levels following thyroidectomy can be almost entirely accounted for by the increase in the hexosamine content of the beta and gamma globulin fractions. The normal distribution of hexosamine in rat plasma is as follows: Albumin 5%, alpha globulins 67%, beta globulins 19%, and gamma globulin 9%. The richest fraction is alpha-1 globulin which contains approximately 4.4% hexosamine. The other globulins contain less and albumin contains only 0.30%.