Action of Norepinephrine on Carotid Sinus Arterial Walls and Blood Pressure. ∗

Abstract

Summary

Local application of norepinephrine to the arterial walls of the carotid sinus induced a marked reflex fall of systemic blood pressure, although the carotid sinus walls were deprived of pressure and pulsatile expansion. Changes not in pulsatile expansion but in tone and tension of the barosensitive arterial walls play a primary and fundamental role in the mechanisms of reflex homeostasis of blood pressure.