Betaine and Methionine on Renal Hemorrhagic Degeneration in Rats Receiving 2-Amino-2-Methyl Propanol-l. ∗

Abstract

Summary

1. The incidence of hemorrhagic kidneys in young male rats on a low choline diet is increaased by the addition of 10 mg of 2-amino-2-methylpropanol-l per gram of food. Choline at a level of 10.76 × 10⁻³ mM per gram of food protects against renal hemorrhagic degeneration caused by 10 mg of 2-amino-2-methylpropanol-l per gram of food. Betaine, methionine, and casein at the levels studied were unable to completely prevent the incidence of kidney lesions caused by 10 mg of 2-amino-2-methylpropanol-l per gram of food.