Abstract
Summary
The Trypanosomid flagellate Crithidia fasciculata was found to have a growth requirement for certain 6-substituted pteridines. The most active compound studied was 2-amino-4-hydroxy-6 (1′, 2′-dihydroxy-propyl) pteridine (“biopterin”) which was isolated from human urine. A requirement for both pteroylglutamic acid and an appropriate pteridine was demonstrated for the organism.
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