An Atypical Electrophoretic Peak in Serum of Patients with Familial Primary Systemic Amyloidosis

Abstract

Summary

Electrophoretic data are presented on 5 related patients with familial primary systemic amyloidosis. The presence of an abnormal peak, located between the a₂ and β globulin fractions, is a consistent finding in these patients. We have arbitrarily called this component a₂. The possible significance of this finding is discussed.