Abstract
Conclusions
1. Pieces of skin 1 cm square were removed from the backs of 2 mature male cynomolgus monkeys. When the sites of excision were 3 to 6 days old, poliomyelitis virus of the Saukett strain was inoculated into the lesions. In the 6 lesions, 3 days old at the time of inoculation, the concentration of virus was minimal at 1 day. Subsequent increase of virus occurred in the case of 4 of these lesions. 2. The amount of virus in the exudate from lesions 5 and 6 days old at the time of inoculation was close to a maximal level at 1 day. At 5 days virus was present in approximately maximal concentration in 11 of the 12 lesions. Virus was present in 7 of the 8 lesions tested for virus one week after inoculation. Extensive healing of wounds had occurred by this time.
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