Abstract
Summary
The effect on EST of the hormones ACTH, cortisone acetate and STH alone and in combination with vasopressin has been investigated. ACTH and cortisone acetate in combination with vasopressin each produced a greater fall in EST than was produced by vasopressin alone. In contrast, STH in combination with vasopressin prevented the fall induced by vasopressin alone and produced its usual elevation in the EST. These observations indicate that the tropic hormones ACTH and STH may modify the response of the central nervous system to vasopressin, possibly through their influence on the adrenal cortex. This interaction of hormonal effects may be involved in the convulsions of eclampsia.
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