Abstract
Summary
Daily doses of 2-3 mg of cortisone acetate injected subcutaneously were without significant effect on the seromucoid hexose polysaccharide in rats after treatment for 14 days. Massive dosages (5-10 mg per day) resulted in significant elevations of seromucoid and slightly lowered serum glycoprotein polysaccharide levels. Starvation resulted in similarly lowered serum glycoprotein levels, but had no significant effect on seromucoid. Injection of turpentine subcutaneously in rats resulted in large elevations of both glycoprotein and seromucoid 4 days after injection. It appears unlikely therefore, that elevations of protein bound carbohydrate following stress can be related to the elaboration of cortisone-like compounds.
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