Analyses of Polymodal Distributions of Nuclear Size Data

Abstract

Summary

Polymodal nuclear size distributions may be analyzed in various ways. Forbes' method and Harding's probability method are applied in this paper. These methodsmay serve to supplement each other and existing methods in providing useful information about a given frequency distribution. 1. Forbes' method of analyzing polymodal distributions may give relatively accurate information about a polymodal nuclear size distribution if a large number of measurements and classes are present. 2. Evidence is presented to show that nuclear sizes in adult mouse liver are based on component normal distributions when plotted on a linear, area, or volume basis. 3. The probability method of analyzing polymodal nuclear size distributions may be used to compare different distributions. A given distribution may further be analyzed by determining the component unimodal curves which contribute to the final distribution.