Abstract
Summary
1. Sheep red blood cells treated with mixtures of purified enterobacterial (E. coli 08 or S. abortus equi) lipopolysaccharides and lecithin, cholesterol, or normal serum were not agglutinated by homologous bacterial antibodies. 2. Pretreatment of erythrocytes with lecithin but not with cholesterol or compatible normal serum had similar effects. 3. The antibody-neutralizing capacity of the lipopolysaccharide-inhibitor mixtures was identical with that of the lipopolysaccharides, as revealed by hemagglutination inhibition tests. 4. It is concluded that the inhibitors interfere with adsorption of enterobacterial lipopolysaccharides by erythrocytes.
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