Autoradiographic Visualization of Ga 45 Intake by Normal and Pathological Cartilage in vitro . ∗

Abstract

Summary

Demineralized sections of normal and pathological cartilage from various sources, were soakes in weak solution of Ca⁴⁵Cl₂ and coated with fluid photographic emulsion. The autoradiographic record has shown an apparently specific pattern of Ca⁴⁵ intake. Comparisons of these images and those obtained with S³⁵04 in vivo and also the negatigating effect of hyluronidase seems to indicate a relationships between Ca⁴⁵ intake and the relative local distribution of sulfated mucop9olysaccharides in the tissue.