Abstract
Summary
Cortisone in a concentration of 0.2 S mg/ml produced a delay and partial inhibition of CP changes when introduced into HeLa cell cultures at the time of infection with poliomyelitis virus Types I and II and with vaccinia virus. This substance appears to have no effect on the virus in the absence of living cells. When cortisone in the same concentration was added to actively growing HeLa cells and then washed away prior to infection, it accelerated the CP changes when cells were subsequently infected with poliomyelitis virus Types I and II.
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