Abstract
Summary
The amino acid, L-canavanine, has been found to inhibit the multiplication of the Lee influenza virus in the chick embryo and even more effectively in tissue culture. It had no direct inactivating effect on the virus. and did not interfere demonstrably with the adsorption of the virus to the host cells. It did not interfere with respiration of the host cells. In tissue culture the inhibitory effect of the compound on the growth of the virus was completely reversed by L-arginine. The implications of these observations with respect to the possible mechanism of inhibition are discussed.
Get full access to this article
View all access options for this article.