Abstract
Summary
Protoveratrine was found to enhance the blood pressure responses to 1-norepinephrine and histamine in dogs and cats. This effect failed to occur in animals whose 9th and 10th nerves were sectioned bilaterally or whose spinal cord was transected. It is suggested that the hypotensive effect of protoveratrine is due to induced spontaneous or repetitive firing of baroceptors, which then become less susceptible to further stimulation or inhibition by changes of pressure.
Get full access to this article
View all access options for this article.