Abstract
Summary
1. Long-time castrated male rats had a mean circulating red blood cell count of 8.70 ‡ .43 million cells/cu mm before treatment. Treatment with testosterone propionate (TP) or nortestosterone cyclopentylpropionate (NTCP) at daily doses of .25 mg or 1 mg for 27 days increased the number of cells to group averages of 9.52 to 10.14 mil-lion/cu mm. Blank-injected controls had RBC counts averaging 8.42 million at the end of the experimental period. 2. Hemoglobin concentration rose from a pretreatment mean of 17.88 g/100 ml to group averages of 19.1 to 20.0 g/100 ml during steroid treatment. Blank-injected controls had 17.8 g/100 ml at the end of the treatment period. 3. It is concluded that nortestosterone cyclopentylpropionate is similar to testosterone propionate in causing increases in red cell count and Hb in the castrate rat.
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