Abstract
Summary
1. Three steroids with protein anabolic activity were tested in parallel with testosterone propionate to compare their relative properties of stimulating the levator ani muscles and seminal vesicles of weanling castrate male rats when injected subcutaneously in oil solution or suspension. The androgenic and myotrophic potencies of the test compounds, as well as their myotrophic/andro-genic ratios, were calculated by analysis of significant portions of the data. 2. The androgenic potencies of these steroids, expressed as percentages of the potency of testosterone propionate, were: methylandrostenediol 2.1, androstanolone 13.2, 19-nortestosterone cyclopentylpropionate 16.2. 3. The myotrophic potencies, expressed as percentages of the potency of testosterone propionate, were: methylandrostenediol 2.2, androstanolone 21.8, 19-nortestosterone cyclopentylpropionate 155. 4. The myotrophic/androgenic ratios of these compounds are, therefore: methylandrostenediol 1.0, androstanolone 1.7, 19-nortestosterone cyclopentylpropinate 9.5.
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