Phosphorylation in Cardiac Muscle from Failing and Unfailing Heart-Lung Preparations. ∗,†

Abstract

Summary

This investigation has demonstrated that there is no difference in phosphorylating ability, i.e., enzyme concentration or activity, between normal cardiac muscle and similar tissue obtained from dog heart-lung preparations. These findings can be considered support for the thesis that if energy metabolism is concerned in failure, the defect is probably not one of production of energyrich compounds.