Abstract
Summary
1. Colchicine injected into normal male rats caused a 70% decrease in circulating eosinophils. Hypophysectomized rats similarly injected with colchicine showed a 50% diminution. 2. Saline injections in normal rats caused a 49% decrease in eosinophils, while in hypophysectomized rats there was an increase of 81%. 3. The eosinopenic response to colchicine appears, in the main, to be due to a direct adrenal stimulation or to a direct peripheral effect.
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