Abstract
Summary
1. The rates of absorption of D(-), L (+), and DL-alanine from the gastrointestinal tract of white rats were found to be 85, 110, and 112 mg/100 g of body weight/ hour, respectively. All 3 were approximately equal in their ability to form liver glycogen, maximum values were obtained 6 hours after administration. Cortisone administration had no effect upon the rate of alanine absorption. 2. When DL-alanine was fed to rats at the same time as 5 or 2.5 mg of cortisone was injected no increase in liver glycogen was obtained over the sum of the amounts formed when each of the substances was given separately. When DL-alanine and cortisone was administered so that the peak of glycogen formation for each compound was reached at the same time then there was a significant increase in glycogen formation over the sum of the independent actions of the 2 compounds.
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