Abstract
Summary
1. Rats irradiated in a hypoxic atmosphere show a slightly higher cellularity and much greater rate of DNA synthesis in the bone marrow and spleen after 96 hours than rats irradiated at ground level. 2. Thirty hours of intermittent hypoxia preceding irradiation at low oxygen tensions does not give additional protection. 3. A striking parallelism exists in the cellular reactions in the bone marrow and spleen following irradiation, both at normal atmospheric pressures and at low oxygen pressure. 4. Irradiation of animals at low oxygen pressures appears to reduce the biological effectiveness of 800 r on the bone marrow to 600 r.
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