Abstract
Summary
Exposure of rats to equal volume dose of x-radiation (200 kg roentgens) through grids having various diameter hole sizes but a constant open area to closed area ratio resulted in increasingly greater survival as the grid hole sizes were decreased. Significantly greater survival was obtained in rats exposed through grids than in rats exposed to total body x-irradiation. It is suggested that these results may be explained by a beneficial local effect of partial shielding whereby normal tissue adjacent to irradiated tissue initiates repair in the irradiated areas. Degree of survival appeared to be directly related to the area of interface between normal and radiated tissue.
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