Abstract
Summary
1. The effect of ovariectomy, adrenalectomy, and hypophysectomy upon growth of spontaneous tumors in mice has been studied. 2. Bilateral adrenalectomy alone or combined with ovariectomy produced a complete regression of the tumor in 3.3% and 3.7% of the mice respectively. Hypophysectomy was followed by regression in 11.5%. of mice. 3. All groups in which either adrenalectomy or hypophysectomy was performed, showed a shorter survival time than unoperated controls, even in those mice showing a complete regression of their tumors.
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