Abstract
Summary
1. Employing the analytical procedure of Nelson and Samuels for plasma 17-hydroxycorticosteroids, it has been shown that the intravenous injection of hydrocortisone in rats produces high concentrations of hormone, followed by a swift return to very low levels. 2. The rapid disappearance of exogenous hydrocortisone from the circulation is prevented by hepatectomy, but nephrectomy and splenectomy exert no appreciable effect.
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