Abstract
Summary
1. Various derivatives of pantothenic acid have been compared for growth promoting activity in A. suboxydans. The order of effectiveness is roughly Co A† = LBF-γ-phosphate >LBF = PA-cysteine (approx.) >PA = pantoic acid >LBF-diphos-phate >PA phosphates, with Co A and LBF-γ-phosphate about 10 to 20 times as active as PA. The derivatives containing -SH groups appear to be active principally, or even exclusively, in the reduced state. 2. It is concluded that the “A. suboxydans stimulatory factor” is multiple in nature, but is not identical with pantothenic acid phosphates.
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