Abstract
Summary
A highly purified preparation of glucagon in doses as high as 0.25 mg/day, has no effect on the width of the epiphyseal cartilage of the hypophysectomized rat as determined by the tibia test for growth hormone. Such a preparation possesses no toxicity when injected into these test animals. Possible reasons for the previously claimed growth promoting activity and toxicity of glucagon fractions are discussed.
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