Abstract
Summary
Dogs subjected to the Wendel operation for mega-esophagus developed severe esophagitis, whereas dogs with the Heller operation did not. 2. Daily injections of histaminme resulted in severe esophagitis in dogs with both the Heller and Wendel operations. 3. Vagotomy alone did not prevent development of esophagitis following the Wendel procedure when the animals recevied histamine. 4. Vagotomy and Pyloroplasty to gether were effective in preventing esophagitis in dogs with the Wendel procedure receiving histamine injections.
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