Abstract
Summary and Conclusions
1. Sera of nongouty and gouty human subjects were subjected to ultrafiltration by 2 different procedures. The urate concentration of ultrafiltrates obtained by means of a Simms-Sanders apparatus did not differ significantly from that of the corresponding sera, expressed as serum water. Low values obtained by the second method employed were found to be factitious. 2. The available data appear to justify the assumption that the plasma urate in man is virtually wholly filtrable at the glomerulus and that some 90% of the filtered urate normally is reabsorbed in the tubules.
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