Abstract
Summary
1. In a study of the development of antibacterial agglutinin, antihemagglutinin, and mouse protective antibody in children convalescing from whooping cough, mouse protective antibody was the only one to occur regularly as a result of the disease; it appears to be the most significant measure of immunity studied. 2. Mouse protective antibody titers increased during convalescence in all instances, the increases generally being from 4- to 10-fold. 3. The intranasal mouse protection test has been found to give reproducible results and is being applied to the study of children immunized against whooping cough.
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