Abstract
Summary
In order to determine the effect of fatigue on susceptibility to experimental poliomyelitis, mice were forced to run in a revolving drum during the day preceding and for 8 hours each day subsequent to the intra cerebral injection of the Lansing strain of virus. Control animals inoculated at the same time with the same amount of virus were allowed to rest in their cages. In all 7 experiments, the incidence of the disease as measured both by paralysis and by death was greater in the exercised animals than in the resting controls.
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