Abstract
Conclusions and Summary
It is evident that the chorioallantoic membranes of chick embryos can oxidize glucose-6-phosphate by an enzyme system similar to that discovered by Warburg and Christian(12,13). The centrifugal supernatant fluid of homogenates contains the complete catalytic system necessary for oxidation of glucose-6-phosphate as measured in our test system. The reaction is completely dependent on hexose-6-phosphate and TPN. This finding is of particular interest since it indicates that the chorioallantoic membrane contains an alternative pathway of glucose metabolism besides the glycolytic system described pre viously (1).
Homogenates of chorioallantoic membranes of the chick embryo oxidize glucoses-phosphate or fructose-6-phosphate aer-obically if TPN and pyocyanine are present. The enzyme activity which is recovered in the centrifugal supernatant fluid does not change appreciably with age of the embryo between 6 and 13 days.
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