Abstract
Summary
Following 6 attacks of acute interstitial pancreatitis in 5 patients and the obstruction of both pancreatic ducts in 9 dogs, the thromboplastic plasma component showed a consistently marked elevation. The significance of this observation is discussed. The increase in plasma fibrinogen concentration in acute pancreatitis was confirmed. Prothrombin did not vary significantly. In addition the levels of plasma coagulation factors in 6 patients with chronic pancreatitis, in 6 dogs with incomplete obstruction of the pancreatic ducts and in 13 normal untreated dogs are reported. The coagulation factors were determined quantitatively on plasma fractions obtained by a low temperature procedure. Amylase determinations were done on all specimens.
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