Inhibition of Chicken Tumor I by Plasma from Chickens Infected with an Avian Malaria Parasite

Abstract

Summary

Two-week-old chickens were inoculated in the breast muscle with a suspension of chicken tumor I tissue. They were subsequently left untreated or given a series of intravenous injections of either normal chicken plasma or plasma from corresponding chickens which were near the peak of an acute infection with Plasmodium lophurae. On the day after the last treatment the tumors which had developed were weighed. In a series of 5 experiments, the mean tumor weight of the chickens left untreated or treated with normal plasma was 1.5 to 1.8 times greater than that of the chickens treated with malarious plasma.