Abstract
Conclusions
1. Crude uncentrifuged rabbit or mouse brain tissue, combined with adjuvant, elicited acute encephalomyelitis in more than 50% of 99 guinea pigs. 2. The encephalitogenic activity of both types of brain tissue was decreased but not eliminated by low speed centrifugation. 3. Protamine sulfate appeared to sediment most, if not all, of the encephalitogenic activity of both rabbit and mouse brain material.
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