Abstract
Summary
1. Aureomycin-HCl in concentrations of 10-100 μg/ml inhibits the reduction to arylamine of the nitro groups of chloramphenicol and p-nitrobenzoic acid by cell-free extracts of E. coli (E-26). 2. Under similar conditions, terramycin has little effect on the reduction. 3. 2,4-dinitrophenol inhibits the reduction of the organic nitro compounds to the same extent as aureomycin. 4. Studies are in progress on the possible similarity in the underlying mechanism of inhibition by aureomycin and dinitrophenol.
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