Effect of Stress on Diurnal Fluctuations in Eosinophils of the Laboratory Mouse. ∗

Abstract

Summary

The well known diurnal fluctuation in the number of circulating eosinophils in mice was maintained in animals exposed to continuous cold. It is suggested that a diurnal cycle of activity is responsible for this variation and that the nocturnal activity, acting as a stress, elicits increased activity from the adrenal cortex which is already responding to the stress of cold.