Abstract
Summary
1. Sharply limited ablation of the arm or leg area of the precentral motor cortex in the macaque produces a complete or partial depression of the reflex myoclonic responses of the affected extremities as elicited after subconvulsant metrazol dosage. This occurs in chronic, as well as acute preparations. 2. When responses are present, there is a predominance of extensor muscle activity, with marked diminution of finger- or toe-flexor responses. A similar pattern is observed when generalized seizures are elicited by repetitive acoustic stimulation.
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