Effect of Vitamin B 12 on Wound Healing ∗

Abstract

Summary

1) These data show that B₁₂ increased the tensile strength of wounds during the early phases of healing in rats fed balanced diets containing 19% or 25% protein. This effect was evident at least by the third day in the wounds studied, and it was most noticeable by the sixth day. 2) The wound's that were studied in the saline control and vitamin treated rats from the third to the eighth day showed no significant diffemnce in their healing rates at the eighth day. 3) The delayed healing rate and increased incidence of wound infection in rats that were protein depleted by, diet were not signifioantly altered by administration of vit. B₁₂.