Abstract
Summary
1. Serum antibody titers have been determined in a passive protection experiment in which rhesus monkeys were inoculated intramuscularly with Lansing antiserum prepared in rhesus monkeys; the monkeys were challenged thalamically with 50 PD50 of Lansing virus. 2. Four of these monkeys developed paralysis, and 9 remained clinically and histologically normal. 3. Average serum antibody titers in samples removed one week after inoculation were 10−1.87 in the paralyzed group, and 10−1.88 in the unaffected group. 4. By extrapolation, the initial antibody titer was estimated to be 10−2.1. The average titer 6 weeks after inoculation was 10−0.29. 5. The rate of decline of antiboyd in the 9 monkeys the survived the cerebral challenge was constant, the half-life being 6.8 days.
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