Abstract
Summary
Heparin-like polysaccharides with high anticoagulant activity have been isolated from 2 species of clams, Mactra spissula and Artica islandica. These purified polysaccharides, termed mactin-A and mac-tin-B, are related to but not identical with mammalian heparin. They possess a greater in vivo activity and a favorable therapeutic index when compared with heparin preparations of equal in vitro activity.
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