Significance of the Neurohypophysis in Regulation of Fluid Balance in the Frog. ∗

Abstract

Summary

1. The hormone content of the frog neurohypophysis is depleted by dehydration of the animal. 2. Normal and hypophy-sectomized frogs become dehydrated at the same rate. Normal frogs, however, regain the body water lost by dehydration more rapidly than do hypophysectomized frogs. 3. These observations suggest that the neurohypophysis plays a physiologically significant role in the regulation of the water balance of the frog.