Abstract
Summary
ATP, ADP, sodium tripolyphosphate and aluminum silicate restored the amplitude of contraction in hearts made hypo-dynamic by reduced calcium, excess potassium, or acetylmethylcholine chloride. In general, ATP was the most effective compound. ATP alone was effective in hearts depressed by N2 plus IAA. ATP and ADP restored the excitability in hearts depressed by excess potassium. None of the 4 compounds had any effect on the freshly excised heart perfused with oxygenated Ringer.
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