Abstract
Summary
The influence of d-tubocurarine, two central nervous system depressants (pentobarbital and chloral hydrate) and two central nervous system stimulants (pentylene-tetrazol and 5-ethyl-5-(l,3 dimethylbutyl) barbituric acid) on the concentrations of inorganic phosphate, phosphocreatine, and ATP in the cerebrum of the rhesus monkey has been investigated. d-Tubocurarine was the only one of these compounds to produce any statistically significant effect. With this agent there was a significant decrease in phospho-creatine content without any alteration in inorganic phosphate or ATP.
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