Abstract
Summary
A bacterial polysaccharide complex, Piromen, was tested for its effectiveness for promoting survival for an arbitrary period of 15 days of rats receiving fatal thermal injuries. An over-all survival of 62% of the rats was observed in this present experiment, regardless of the route of administration, the regimen of administration, and the size of the dose of the drug. No placebo-treated animal survived longer than 8 days and 95% of them died in 12 hours. Results of the present experiments indicate a dose-weight relationship necessary for survival. When such a relationship was recognized and optimum dosage of Piromen was administered to rats, 87% of the treated animals survived.
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