Abstract
Summary
Intraocular hypophysial transplants in hypophysectomized mice did not maintain body weight or the weights of thyroid, ovaries, adrenals, or uterus significantly above those of hypophysectomized controls. Nevertheless, the implants were able to maintain a radioiodine uptake per unit thyroid weight and a thyroid serum iodide ratio at 2/3 the level of the intact controls. This indicates that thyroid function and thyroid size are not necessarily correlated in the mouse and that the former can be maintained to considerable degree in the absence of the normal hypophysial anatomical relationship.
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