Abstract
Summary
The response of the uteri of ovariectomized mice to a total amount of 0.0054 μg progesterone was inhibited by the simultaneous administration of 0.0240 to 0.030 μ 4-amino pteroylglutamic acid. Aminopterin (4-amino PGA) showed no selective inhibition for estrogen or progesterone when combined with these two steroids, but inhibited both of these compounds when injected within a ligated segment of the uterus of ovariectomized mice according to the method of Hooker and Forbes.
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