Inability of Growth Hormone to Prevent the Anemia which Follows Hypophysectomy. ∗

Abstract

Summary

In the search for the factor in the anterior pituitary responsible for maintenance of the circulating red cell volume, the effect of growth hormone in maintaining the red cell volume of hypophysectomized rats was investigated. Administration of doses of growth hormone sufficient to maintain a normal rate of growth for 30 days failed to prevent the development of the anemia which characteristically follows hypophysectomy.