Abstract
Summary
1. When NDV and Ehrlich were mixed at 4°, 25° and 37° and inoculated immediately, a much smaller percentage of tumors grew than in the NAF control mixtures. When the same mixtures were held at 25° or transferred from 4° to 25° for one to 3 hours, inoculation resulted in tumor growth. 2. When virus and tumor were mixed in vivo no tumor inhibitory effect was noted unless the virus was given intraperitoneally first and the tumor suspensions by the same route immediately thereafter. The course of development of ascites in mice was not affected by daily inoculations of NDV. 3. No evidence could be found for multiplication of the virus in the tumor cells either in the animal or tissue culture.
Get full access to this article
View all access options for this article.