Abstract
Summary
The effects of peptone shock (with and without block of the reticuloendothelial system by India ink), and administrations of desoxycorticosterone on the nonspecific hyaluronidase inhibitor and heparin concentrations in the blood serum of rabbits at intervals before and after the treatments were observed. A general parallelism was noted in the direction of the changes produced in both serum factors, but variations were observed with respect to the magnitude and time of change. In vitro experiments were carried out on the effect of janus green, thionin, toluidene blue, safranin, neutral violet, neutral red, and aureomycin on the serum inhibitor and on hyaluronidase. A general correlation was observed between the anti-heparin action of these substances and their anti-inhibitor effects.
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