Abstract
Summary and conclusions
1. Modifications of Northrop's method of potentiometric titration of chloride are presented which retain its great convenience while eliminating interference from urates. 2. Analyses can be completed at the rate of 20 to 30 per hour, using aliquots of 0.1 to 1.0 ml, with a precision of better than 1%. 3. Accuracy of at least 1% for urine chloride determinations is evidenced by analysis of known solutions of NaCl, recovery of both KCl and NaCl added to urine specimens, and comparison of the values with those obtained by standard methods. 4. The method appears satisfactory for the analysis of evaporated milk preparations without modification: giving accurate recovery of added chloride, better consistency than reference methods, and as good agreement with them as their own variation (up to 5%) will allow. 5. The apparent unsuitability of the method for unmodified serum is discussed briefly.
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